Developing Neutrophils Must Eat…Themselves!
نویسندگان
چکیده
منابع مشابه
P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophils
Under physiological shear stress, neutrophils roll on P-selectin on activated endothelial cells or platelets through interactions with P-selectin glycoprotein ligand-1 (PSGL-1). Both P-selectin and PSGL-1 are extended molecules. Human P-selectin contains an NH2-terminal lectin domain, an EGF domain, nine consensus repeats (CRs), a transmembrane domain, and a cytoplasmic tail. To determine wheth...
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ژورنال
عنوان ژورنال: Immunity
سال: 2017
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2017.08.013